Although pomegranate juice is generally considered safe during pregnancy if it is pasteurized, according to Livestrong, it may interact negatively with some medications. Pregnant women should consult with their doctor prior to drinking pomegranate juice about this. Also pregnant women with gestational diabetes should also consult with their doctor about the safety of pomegranate juice in their diet.
Additionally, WebMD states that fresh-squeezed juice may not always be pasteurized, which means that harmful bacteria like Salmonella and E. Coli may be present in the juice. Pregnant women should avoid fresh juice without a label stating that it is pasteurized.